Genome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics

ChEBI2013-04-18 更新2026-07-21 收录

表观遗传修饰动力学

DNA去甲基化机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-42250 数据链接链接失效反馈

官方服务：

资源简介：

Genome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics

创建时间：

2013-04-18

UHRF2 Commissions the Accomplishment of DNA Demethylation through Allosteric Activation by 5hmC and K33-linked Ubiquitination of XRCC1

DNA去甲基化机制

表观遗传调控

The transition of oxidized 5-methylcytosine (5mC) intermediates into base excision repair (BER) pipeline to complete DNA demethylation remains enigmatic. We report here that UHRF2, the only paralog of

NIAID Data Ecosystem50

Fam60a is a component of the mSin3A-HDAC transcriptional corepressor complex and inhibits Tet-mediated DNA demethylation

发育表观遗传调控

DNA去甲基化机制

Fam60a was identified as a highly expressed gene of unknown function in mouse embryonic stem cells. We have examined the role of Fam60a in mouse development. Most Fam60a mutant embryos manifest hypopl

NIAID Data Ecosystem40

Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer. Monotherapy of the DNA Hypomethylating Agent, NTX301 Targets Ovarian Cancer

卵巢癌药物靶向治疗

DNA去甲基化机制

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

Active DNA demethylation promotes cell fate specification and the DNA damage response [SEAL]

DNA去甲基化机制

细胞命运决定

Neurons harbor high levels of endogenous single strand DNA breaks (SSBs) that are targeted to neuronal enhancers and correlate with marks of DNA demethylation. To determine the source of SSBs at neuro

NIAID Data Ecosystem50

Somatic DNA demethylation generates tissue-specific methylation states and impacts flowering time [BiSulfite-seq]

DNA去甲基化机制

开花时间调控

Cytosine methylation is a reversible epigenetic modification to DNA. In plants, removal of cytosine methylation is accomplished by the four members of the DME family of 5-methylcytosine DNA glycosylas

NIAID Data Ecosystem20

Genome-wide analysis reveals TET- and TDG-mediated 5-methylcytosine oxidation dynamics

资源简介：

相关数据集