Resistance of DEPN-8+1.5% by weight Mini-B to degradation by phospholipase A2 (PLA2) compared to calf lung surfactant extract (CLSE).

Data are mean±SEM for n = 3. DEPN-8+1.5% by weight Mini-B was incubated in vitro with PLA2 (0.1 Units/ml) for 30 min at 37°C, and degradation was assessed by measuring lipid classes in weight percent based on phosphate analysis of bands on thin layer chromatography. Results for CLSE in the presence and absence of PLA2 utilized identical methods as reported previously by Wang et al [30].