Formation of amyloid-like fibrils is involved in numerous human protein deposition diseases, but is also an intrinsic property of polypeptide chains in general. Progress achieved recently now allows t
Protein aggregation is the phenomenon which occurs when misfolded or unfolded protein physically binds together and can cause the development of various amyloidosis diseases. The goal of this study wa
Supplementary data and metadata for Aggrescan4D: structure-informed analysis of pH-dependent protein aggregation Oriol Bárcenas, Aleksander Kuriata, Mateusz Zalewski, Valentín Iglesias, Carlos Pint
The uploaded data has been divided into six different classes including Amyloid fibril forming hexa-peptides, Amorphous β-aggregating hexa-peptides, Amyloid fibril forming peptides ofdifferent lengths
The purpose of this work was to construct a consensus prediction algorithm of ‘aggregation-prone’ peptides in globular proteins, combining existing tools. This allows comparison of the different algor