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A genome-wide CRISPR/Cas9 screen identifies therapeutic targets required for the tumorigenesis of ovarian clear cell carcinoma (OCCC).

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NIAID Data Ecosystem2026-03-13 收录
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To identify genes critical for the proliferation of ovarian clear cell carcinoma (OCCC), we performed CRISPR/CAS9 screens against the OCCC cell lines OVICE, ES2, TOV21G and JHOC5 using the TKOv3 sgRNA library. Overall design: Genome-wide CRISPR/Cas9 screen of OVISE, TOV21G, ES2 and JHOC5 (ovarian cancer cell) using the Toronto KnockOut (TKO) CRISPR Library (TKOv3). 2 biological replicates (OVISE, TOV21G, ES2) and 1 biological replicate (JHOC5).

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2022-07-08
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