Post-treatment malaria transmission in relation to mutations in the dhfr and dhps genes.

IQR = interquartile range; Non-ACT = treatment with sulphadoxine-pyrimethamine (SP) alone or in combination with amodiaquine; ACT = treatment with SP and artesunate (3 days).¥Gametocyte densities were measured by Pfs25 QT-NASBA.*Mutations were determined at enrolment: double mutation = mutations in c108+c59 or c108+c51; ≥ three mutations = mutations in c51+c59+c108 and possible additional mutations;§estimates were adjusted for correlation between observations from the same individual.四分位距（interquartile range, IQR）；非青蒿素联合疗法（Non-ACT）指单用磺胺多辛-乙胺嘧啶（SP）或联合阿莫地喹治疗；青蒿素联合疗法（ACT）指采用磺胺多辛-乙胺嘧啶与青蒿琥酯联用的3天疗程治疗方案。¥配子体密度通过Pfs25定量核酸序列扩增法（Pfs25 QT-NASBA）测定。*入组时确定突变类型：双重突变指c108位点与c59位点突变，或c108位点与c51位点突变；≥3种突变指c51、c59、c108位点突变及可能存在的额外突变；§评估值已针对同一受试者的观测值之间的相关性进行校正。