Post-Hoc Contrast for “Abnormal VTA/SN” MDD Subgroup (10 MDD Versus 10 Matched Controls).

Positive t values indicate FA values were elevated in MDD subjects relative to control subjects; negative t values indicate FA values were reduced in MDD subjects relative to control subjects. p values are reported uncorrected; symbols indicate significance and trends at the corrected threshold. *p value met the corrected threshold. †p value was within an order of magnitude of the corrected threshold (a trend). Abbreviations: R: right hemisphere; L: left hemisphere; wm: white matter; gm: gray matter; VTA/SN: ventral tegmental area/substantia nigra; DLPFC: dorsolateral prefrontal cortex; FOC: orbitofrontal cortex; SGC: subgenual cortex; PMC: premotor cortex; CCtx: calcarine cortex; MDM/PAG: medial dorsal midbrain/periaqueductal gray.