Supplementary data 1:Fasta file of tlr3 gene sequences in new world and old world primates

A comparison of genomic sequences of tlr3 derived from old world and new world primate species, consisting of black snub-nosed monkey (Rhinopithecus bieti), drill (Mandrillus leucophaeus), olive baboon (Papio anubis), vervet-AGM (Chlorocebus sabaeus), sooty mangabey (Cercocebus atys), Bolivian squirrel monkey (Saimiri boliviensis boliviensis), Ma's night monkey (Aotus nancymaae), white-tufted-ear marmoset (Callithrix jacchus), and bamboo lemur (Hapalemur griseus), alongside the Tarsier (Carlito syrichta) outgroup. This dataset was used to investigate the molecular mechanisms underlying the antiviral response to Zika virus seen in these primate species. The comparison reveals similarities and differences in the genomic sequences, providing valuable insights into the evolution of primate immune systems. The figure underscores the importance of genomic studies for unraveling the complex interplay between viruses and their host's immune systems.

本数据集包含来自旧世界与新世界灵长类物种的TLR3（Toll样受体3）基因组序列，涉及物种包括滇金丝猴（Rhinopithecus bieti）、鬼狒（Mandrillus leucophaeus）、橄榄狒狒（Papio anubis）、黑长尾猴-AGM（Chlorocebus sabaeus）、乌灰白眉猴（Cercocebus atys）、玻利维亚松鼠猴（Saimiri boliviensis boliviensis）、马氏夜猴（Aotus nancymaae）、白簇耳狨猴（Callithrix jacchus）、竹狐猴（Hapalemur griseus），并以菲律宾眼镜猴（Carlito syrichta）作为外类群。本数据集被用于探究上述灵长类物种针对寨卡病毒的抗病毒应答背后的分子机制。该序列比对揭示了基因组序列间的异同，为灵长类免疫系统的演化提供了宝贵见解。本数据集配图阐明了基因组研究在解析病毒与宿主免疫系统间复杂互作关系时的重要价值。