Laboratory evolution of dihydrofolate reductase (DHFR)

NIAID Data Ecosystem2026-03-14 收录

定向进化

蛋白质工程

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA923701 数据链接链接失效反馈

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资源简介：

We performed laboratory evolution of murine dihydrofolate reductase (DHFR) and sequenced populations from rounds 1-5 and 15.

创建时间：

2023-01-13

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酶结构解析

蛋白质工程

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Initial model selection criteria and goal of each of the four EndoS2-Fc-glycan models.

抗体糖基化建模

蛋白质工程

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蛋白质工程

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Rational Design and Directed Evolution of E. coli Apartate Aminotransferase to Tyrosine Aminotransferase: Mutant P2.

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STRUCTURE OF A THERMOSTABLE DISULFIDE-BRIDGE MUTANT OF PHAGE T4 LYSOZYME SHOWS THAT AN ENGINEERED CROSSLINK IN A FLEXIBLE REGION DOES NOT INCREASE THE RIGIDITY OF THE FOLDED PROTEIN

蛋白质工程

结构生物学

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Protein Data Bank Japan2024-10-30 更新50

Engineering a closed form of the Archaeoglobus fulgidus ferritin by site directed mutagenesis

蛋白质工程

结构生物学

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Protein Data Bank Japan2023-09-06 更新40

Laboratory evolution of dihydrofolate reductase (DHFR)

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