Additional file 4 of Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities

Additional file 4: Table S4. KMT2D ChIP-MS results. A. KMT2D ChIP-MS detected proteins. Accession: uniprot id. Gene: hugo gene symbol. LogFC_HL_kmt2d_R1KO1: log10 fold change (heavy isotope/light isotope) of replicate 1 of HEK-KMT2DKO1. LogFC_HL_kmt2d_R2KO1: log10 fold change (heavy isotope/light isotope) of replicate 2 of HEK-KMT2DKO1. LogFC_HL_kmt2d_R1KO3: log10 fold change (heavy isotope/light isotope) of replicate 1 of HEK-KMT2DKO3. LogFC_HL_kmt2d_R2KO3: log10 fold change (heavy isotope/light isotope) of replicate 2 of HEK-KMT2DKO3. Num_reps_with_peptides: number of replicates with peptides detected. B. Enriched GO biological processes found among detected proteins. Results are outputs from ClusterProfiler. C. Clustered GO terms. D. A list of KMT2D interactors that overlap with KMT2D co-/anti-essential genes.