Identification of Rfx6-regulated genes in mouse embryonic small intestine endocrine cells by microarrays. Identification of Rfx6-regulated genes in mouse embryonic small intestine endocrine cells by microarrays

To identify genes regulated by Rfx6 in the mouse small intestine endocrine cells we performed microarrays gene profiling Overall design: To identify genes regulated by Rfx6 in small intestine endocrine cells we generated mice with an endocrine-specific deletion of Rfx6. Therefore we crossed Rfx6f/f mice (Piccand et al. Cell Reports 2014) with Ngn3-Cre mice (Takakura et al. Dev. Biol. 2004). The small intestine of control (Rfx6f/+; Rfx6f/f) or mutant (Rfx6f/f, Ngn3-Cre) mice were harvested at embryonic stage E18.5.