Prevalence and factors associated with metabolic syndrome in 6-10-year-old children

Abstract Aims: to identify the prevalence of metabolic syndrome (MetS) and associated risk factors in children. Methods: a total of 1,480 Brazilian children aged 6-10 years old (52.2% girls) participated in this population-based, epidemiological cross-sectional study. The inclusion criteria were children born between the years 2001 and 2006, of both sexes, who did not use remedy, were not on a calorie restriction diet, and who respected the 12-hour fast for blood collection. Anthropometric measurements, blood pressure, blood collection, and completion of the Previous Day Food Questionnaire and interview using a Physical Activity List were held at school. Parents were asked to complete a questionnaire on socioeconomic status and lifestyle habits of their child. Chi-square test compared proportions and factors associated with MetS were identified using Poisson Regression. Results: Girls had significantly higher MetS prevalence compared with boys (12.6% vs. 8.5%, p=0.046). After multivariable analysis, body fat percentage (p=0.001), fat mass (p摘要 研究目的：明确儿童代谢综合征（Metabolic Syndrome, MetS）的患病率及其相关危险因素。方法：本研究为基于人群的流行病学横断面研究，共纳入1480名6~10岁巴西儿童（女性占比52.2%）。纳入标准为2001至2006年间出生的男女儿童，未服用药物、未进行热量限制饮食，且采血前需禁食12小时。人体测量指标检测、血压测量、血液采集、前一日食物问卷填写以及采用体力活动清单开展的访谈均在学校完成。家长需填写关于儿童社会经济状况与生活习惯的调查问卷。采用卡方检验比较各组比例，通过泊松回归分析识别与MetS相关的危险因素。结果：女性代谢综合征患病率显著高于男性（12.6% vs. 8.5%，p=0.046）。经多变量分析后，体脂百分比（p=0.001）、脂肪量（p