Prevalence and levels of autoantibodies in cerebrospinal fluid from patients with NPSLE and controls.

NPSLE = neuropsychiatric systemic lupus erythematosus; SLE-surgical = lupus patients who underwent elective surgery; SLE-septic meningitis = lupus patients with septic meningitis, Non-autoimmune = patients without autoimmune diseases.1P2P3P4P = 0.006 versus SLE-septic meningitis5P6P7The NMDAR antibody was measure in 34 SLE-CNS patients, 5 SLE-PNS, 12 SLE-surgical, 5 SLE-septic meningitis, and 25 Non-autoimmune patients.8Autoantibodies levels represent the mean (±SD) among the patients in whom they were positive. The number of patients in each group for a particular antibody corresponds to the prevalences displayed in the upper panel.NPSLE = 神经精神性系统性红斑狼疮（neuropsychiatric systemic lupus erythematosus）；SLE-surgical = 接受择期手术的狼疮患者；SLE-septic meningitis = 合并脓毒性脑膜炎的狼疮患者；Non-autoimmune = 无自身免疫性疾病的患者。P1、P2、P3、P4与SLE-septic meningitis组的比较P值为0.006；P5、P6、P7。本研究共检测了34例SLE-CNS（系统性红斑狼疮中枢神经系统受累）患者、5例SLE-PNS（系统性红斑狼疮外周神经系统受累）患者、12例接受择期手术的狼疮患者、5例合并脓毒性脑膜炎的狼疮患者以及25例无自身免疫性疾病患者的N-甲基-D-天冬氨酸受体（N-methyl-D-aspartate receptor, NMDAR）抗体水平。自身抗体水平以阳性患者的均值±标准差表示。某一特定抗体在各组中的患者数量对应于上方图表中展示的患病率。