Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol

Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[4-(2-hydroxyethyl)cyclohexylidene]methanediyl}diphenol Descriptor: 4,4'-({4-[2-(4-fluorobutoxy)ethyl]cyclohexylidene}methanediyl)diphenol, Estrogen receptor, Nuclear receptor coactivator 2 Authors: Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. Deposit date: 2015-09-29 Release date: 2016-05-04 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016

与环芬尼衍生物4,4'-{[4-(2-羟乙基)亚环己基]亚甲基二}二苯酚结合的雌激素受体α（ER-α）配体结合结构域晶体结构
描述物：4,4'-({4-[2-(4-氟丁氧基)乙基]亚环己基}亚甲基二)二苯酚、雌激素受体（Estrogen Receptor）、核受体辅激活因子2（Nuclear receptor coactivator 2）
作者：Nwachukwu, J.C.、Srinivasan, S.、Zheng, Y.、Wang, S.、Min, J.、Dong, C.、Liao, Z.、Cavett, V.、Nowak, J.、Houtman, R.、Carlson, K.E.、Josan, J.S.、Elemento, O.、Katzenellenbogen, J.A.、Zhou, H.B.、Nettles, K.W.
提交日期：2015-09-29
发布日期：2016-05-04
最后修改日期：2023-09-27
方法：X射线衍射（分辨率2.1埃）
引用：《通过雌激素受体介导配体特异性信号传导的预测特征》，Mol.Syst.Biol.，第12卷，2016年