Sequential one-pot procedure “Asymmetric Allylic Alkylation catalyzed by a Lewis Base and Gold catalyzed Friedel-Crafts cyclization”: NMR data of pure compounds

The synthesis of functionalized chiral heteroaromatic polycyclic compounds was performed by leveraging two unfriendly catalytic cycle in a one-pot sequential process. α-Heteroaromatic-γ-butyrolactones were first engaged in a highly regio-, diastereo- and enantiostereoselective Lewis base asymmetric allylic alkylation with alkyne functionalized Morita−Baylis− Hillman (MBH) carbonates. Gratefully to the low Lewis base catalyst loading, subsequent gold catalyzed Friedel-Crafts cyclization, entailing the formation of fused polycyclic compounds, proceeded efficiently affording structurally complex highly enantioenriched products. These data are the primary NMR FID files of all new compounds of this study.