Additional file 1 of Genetic liability to obesity and peptic ulcer disease: a Mendelian randomization study

Additional file 1. Tabel S1. Proxies for SNPs not found in the outcome dataset (Forward MR); Tabel S2. Characteristics of the genetic variants associated with body mass index; Tabel S3. Characteristics of the genetic variants associated with waist-to-hip ratio; Tabel S4. Characteristics of the genetic variants associated with body mass index in replication analyses; Tabel S5. Characteristics of the genetic variants associated with waist-to-hip ratio in replication analyses; Tabel S6. Proxies for SNPs not found in the outcome dataset (Reverse MR); Tabel S7. Characteristics of the genetic variants associated with peptic ulcer disease; Tabel S8. Evaluation of heterogeneity and directional pleiotropy using different methods (Forward MR); Tabel S9. Evaluation of heterogeneity and directional pleiotropy in replication analyses (Forward MR); Table S10. Associations of genetic predisposition to PUD with risk of obesity in complementary Mendelian Randomization analyses (Reverse MR); Tabel S11. Evaluation of heterogeneity and directional pleiotropy using different methods (Reverse MR); Tabel S12. Evaluation of heterogeneity and directional pleiotropy in replication analyses (Reverse MR).附加文件1。表S1：未在结局数据集内检出的单核苷酸多态性（Single Nucleotide Polymorphisms, SNPs）替代位点（正向孟德尔随机化，Forward MR）；表S2：与体质量指数相关的遗传变异特征；表S3：与腰臀比相关的遗传变异特征；表S4：重复分析中与体质量指数相关的遗传变异特征；表S5：重复分析中与腰臀比相关的遗传变异特征；表S6：未在结局数据集内检出的SNPs替代位点（反向孟德尔随机化，Reverse MR）；表S7：与消化性溃疡病（Peptic Ulcer Disease, PUD）相关的遗传变异特征；表S8：采用多种方法评估异质性与定向多效性（正向孟德尔随机化，Forward MR）；表S9：重复分析中采用多种方法评估异质性与定向多效性（正向孟德尔随机化，Forward MR）；表S10：互补孟德尔随机化（反向孟德尔随机化，Reverse MR）分析中消化性溃疡病遗传易感性与肥胖风险的关联；表S11：采用多种方法评估异质性与定向多效性（反向孟德尔随机化，Reverse MR）；表S12：重复分析中采用多种方法评估异质性与定向多效性（反向孟德尔随机化，Reverse MR）