Single-nucleotide–level mapping of DNA regulatory elements that control fetal hemoglobin expression (RNA-Seq). Single-nucleotide–level mapping of DNA regulatory elements that control fetal hemoglobin expression (RNA-Seq)

gRNA screening for HbF+ and HbF- samples were performed to identify candidate cis-regulatory elements. Overall design: CRISPR pooled gRNA screening, RNA-seq, ChIP-seq and ATAC-seq were performed