Cytokine production by TLR4lig-Pp3 and TLR4lig

Production of cytokine into the culture supernatant. In the case of TLR4, only significant increases of IL-5 were observed in allergic patients compared to tolerant controls when stimulating with TLR4lig-Pp3 and TLR4lig plus Pp3 peptide in separately way. No differences in the induction of IL-10 production were observed in allergic patients compared to tolerant controls

细胞因子向细胞培养上清液中的分泌水平。针对Toll样受体4（TLR4），仅在分别使用TLR4配体-Pp3（TLR4lig-Pp3）以及TLR4配体联合Pp3肽进行刺激时，过敏性患者组的白细胞介素-5（IL-5）水平较耐受对照组呈现显著升高。而过敏性患者组与耐受对照组在白细胞介素-10（IL-10）的诱导产生水平上未观察到显著差异。