Driver mutations under hypoxia.

Targeted proteins and corresponding mutations that enable the network to evade apoptosis induced by hypoxia. The efficacy of a mutation was defined as the fraction of initial states that are driven to the new phenotype.可使该网络逃逸低氧（hypoxia）诱导的细胞凋亡（apoptosis）的靶向蛋白及其对应突变体。突变的效力被定义为被驱动至新表型（phenotype）的初始状态所占的比例。