PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z4439011520 (Mpro-x2694)

PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen -- Crystal Structure of SARS-CoV-2 main protease in complex with Z4439011520 (Mpro-x2694) Descriptor: 3C-like proteinase, DIMETHYL SULFOXIDE, N-(5-tert-butyl-1,2-oxazol-3-yl)-N-[(1R)-2-[(4-methoxy-2-methylphenyl)amino]-2-oxo-1-(pyridin-3-yl)ethyl]propanamide Authors: Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. Deposit date: 2020-05-15 Release date: 2020-05-27 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.72 Å) Cite: PanDDA analysis group deposition SARS-CoV-2 main protease fragment screen To Be Published

PanDDA分析小组存档的严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）主蛋白酶片段筛选数据集——与Z4439011520（Mpro-x2694）结合的SARS-CoV-2主蛋白酶晶体结构。描述符：3C样蛋白酶（3C-like proteinase）、二甲基亚砜（dimethyl sulfoxide）、N-(5-叔丁基-1,2-恶唑-3-基)-N-[(1R)-2-[(4-甲氧基-2-甲基苯基)氨基]-2-氧代-1-(吡啶-3-基)乙基]丙酰胺。作者：Fearon, D、Owen, C.D、Douangamath, A、Lukacik, P、Powell, A.J、Strain-Damerell, C.M、Resnick, E、Krojer, T、Gehrtz, P、Wild, C、Aimon, A、Brandao-Neto, J、Carbery, A、Dunnett, L、Skyner, R、Snee, M、London, N、Walsh, M.A、von Delft, F.。存档日期：2020-05-15；发布日期：2020-05-27；最后修改日期：2026-02-18。实验方法：X射线衍射（分辨率1.72埃）。引用：PanDDA分析小组存档的SARS-CoV-2主蛋白酶片段筛选数据集，待发表。