daf-2 or insulin signaling pathway
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Insulin receptor pathway in C. elegans Initial version based on review by [https://www.ncbi.nlm.nih.gov/pubmed/16441841 Gami and Wolkow] of pathways that affect ageing. The DAF-2 gene encodes for the insulin-like growth factor 1 (IGF-1) receptor in the worm Caenorhabditis elegans. C. elegans with a diet of low glucose, reduced Daf-16 activity and worms lifespan was shortened compared to worms fed on media without glucose.
基于Gami和Wolkow对影响衰老通路之综述[https://www.ncbi.nlm.nih.gov/pubmed/16441841],本数据集旨在探讨秀丽隐杆线虫(Caenorhabditis elegans)的胰岛素受体通路。DAF-2基因编码线虫体内的胰岛素样生长因子1(IGF-1)受体。与摄食无葡萄糖饮食、DAF-16活性降低且寿命缩短的线虫相比,摄食不含葡萄糖培养基的线虫寿命有所延长。
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