Prevalence of enteropathogens in the feces of children attending day care from March 2010 through March 2013 in the Netherlands.

*The total number of fecal samples positive for a specific enteropathogen divided by the total number of fecal samples analyzed.**Prevalence estimates are based on a 0–2 year old child with no gastrointestinal symptoms sampled during the winter in the year 2011/2012 using pathogen-specific multilevel mixed-effects (MME) logistic regression models. These models were fitted with two random-effects, one at the level of the DCC and one at the level of the individual child, and were used to estimate the associations between the age, season, year and gastrointestinal symptoms at time of sampling and the presence of the enteropathogen under study. Using the fitted MME logistic regression models, we estimated the enteropathogen prevalence in the feces of an asymptomatic child aged of 0–2 years old during the winter season in 2011/2012.***Significant odds ratios (ORs) are indicated in boldface.****Given the small number of detections the crude, rather than the estimated, prevalence, is given.*某特定肠道病原体（enteropathogen）检测阳性的粪便样本总数，除以所分析的粪便样本总数量。*本患病率估算基于2011/2012年冬季采样的无胃肠道症状0至2岁儿童人群，采用病原体特异性多水平混合效应（multilevel mixed-effects, MME）逻辑回归模型。该模型设置两个随机效应层级：其一为DCC层级，其二为个体儿童层级，用于估算采样时的年龄、季节、年份、胃肠道症状与所研究肠道病原体检出情况之间的关联。通过拟合得到的MME逻辑回归模型，我们估算了2011/2012年冬季无症状0至2岁儿童粪便中的肠道病原体患病率。*具有统计学意义的比值比（odds ratio, OR）以粗体标注。*鉴于检出例数较少，此处给出的是粗患病率而非估算患病率。