Table_1_Files_Performance
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MOBHunter, a pipeline combining 10 high-performing tools and custom algorithms to detect unique genomic regions, diagnostic markers and genetic boundaries of MGE. MOBHunter integrates these predictions, offers evidence-based classifications, and produces GenBank-compatible outputs for visualization, creating a comprehensive platform for MGE analysis of complete genomes of bacteria and archaeas.The process starts with the pipeline setting the environment in which it will work. The script checks for the availability of .gbk files in the defined path. Then, it will proceed to convert the .gbk files into formats required by the other programs. Converted formats include .faa, .ffn, .fna and .ptt.After the required files are created, the pipeline will run all the incorporated 10 programs. The outputs are then processed in a consensus, and the consensus will conduct the scoring of each hit. If a hit is classified by all the incorporated programs, it will receive a higher score.
MOBHunter是一款整合10款高性能工具与自定义算法的分析流程,用于检测可移动遗传元件(Mobile Genetic Element, MGE)的独特基因组区域、诊断标记及遗传边界。该流程整合各类预测结果,提供基于证据的分类功能,并生成兼容GenBank格式的输出文件以支持可视化操作,从而构建起一套可全面分析细菌与古菌完整基因组的可移动遗传元件分析平台。 分析流程首先配置运行环境,脚本会检查指定路径下的.gbk格式文件是否存在。随后,流程将.gbk格式文件转换为其他程序所需的格式,包括.faa、.ffn、.fna以及.ptt格式文件。 待所需格式的文件生成完成后,流程将运行全部集成的10款工具。之后会对所有输出结果进行一致性处理,并基于一致性结果对每一处命中进行评分。若某一处命中被所有集成工具共同判定,则可获得更高评分。



