Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(1-benzothiophen-3-ylsulfonyl)-3-(5-bromo-1,3-thiazol-2-yl)urea

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(1-benzothiophen-3-ylsulfonyl)-3-(5-bromo-1,3-thiazol-2-yl)urea Descriptor: Fructose-1,6-bisphosphatase 1, N-[(5-bromo-1,3-thiazol-2-yl)carbamoyl]-1-benzothiophene-3-sulfonamide Authors: Ruf, A, Joseph, C, Alker, A, Banner, D, Tetaz, T, Benz, J, Kuhn, B, Rudolph, M.G, Yang, H, Shao, C, Burley, S.K. Deposit date: 2017-04-18 Release date: 2019-01-09 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(1-benzothiophen-3-ylsulfonyl)-3-(5-bromo-1,3-thiazol-2-yl)urea To be published

人源肝脏果糖-1,6-双磷酸酶1（fructose-1,6-bisphosphatase 1，果糖1,6-双磷酸1-磷酸酶，E.C.3.1.3.11）与变构抑制剂（allosteric inhibitor）1-(1-苯并噻吩-3-基磺酰基)-3-(5-溴-1,3-噻唑-2-基)脲的复合物。描述符：果糖-1,6-双磷酸酶1，N-[(5-溴-1,3-噻唑-2-基)氨基甲酰基]-1-苯并噻吩-3-磺酰胺。作者：Ruf, A、Joseph, C、Alker, A、Banner, D、Tetaz, T、Benz, J、Kuhn, B、Rudolph, M.G、Yang, H、Shao, C、Burley, S.K.。沉积日期：2017-04-18；发布日期：2019-01-09；最后修改日期：2024-03-06。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率2.2 Å。引用说明：人源肝脏果糖-1,6-双磷酸酶1（fructose-1,6-bisphosphatase 1，果糖1,6-双磷酸1-磷酸酶，E.C.3.1.3.11）与变构抑制剂（allosteric inhibitor）1-(1-苯并噻吩-3-基磺酰基)-3-(5-溴-1,3-噻唑-2-基)脲的复合物（待发表）