Aducanumab Fc dead bulk RNAseq
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP538938
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The aim of this study was to investigate the effect of aducanumab with and without Fc effector function (Fc dead) on APP/PS1 amyloid mice. Male mice 41-57 weeks were treated with two 40 mg/kg doses, spaced two weeks apart, of either aducanumab, Fc dead aducanumab, or IgG control. Mice were harvested 1 week after the final dose. RNA was extracted from snap frozen forebrains with the Qiagen RNeasy Mini Plus Kit. Library preparation and sequencing were performed by Novogene.
创建时间:
2025-11-12



