five

Impact of intestinal bacteria on DNA methylation and tumorigenesis

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP649385
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We utilized two different groups of GF Apc Min/+ mice and colonized them with two differentconsortia, one harboring a pks + E. coli strain with "low-pks" activity (DSMZ) and the second with aclinical isolate exhibiting "high-pks" activity (UM149). Mice were colonized with the differentconsortia, exposed to DSS-induced colitis, and analyzed for tumor burden, DNA methylation, andtranscriptional changes.
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2026-02-13
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