Nanocurcumin

Obesity as part of metabolic syndrome is a major lifestyle disorder throughout the world. Current drug treatments for obesity produce small and usually unsustainable decreases in body weight with the risk of major adverse effects. Surgery has been the only treatment producing successful long-term weight loss. As a different but complementary approach, lifestyle modification including the use of functional foods could produce a reliable decrease in obesity with decreased comorbidities. Our research includes functional foods such as berries, vegetables, fibre-enriched grains and beverages such as tea and coffee. Our studies also focus on development of animal models of inflammatory diseases such inflammatory bowel disease, chronic kidney disease and arthritis. These models are then used to investigate the effects of functional foods in attenuation of these disorders.

作为代谢综合征（metabolic syndrome）的组成部分，肥胖是全球范围内一类主要的生活方式相关性疾病。当前针对肥胖的药物治疗仅能实现小幅且通常难以持续的体重下降，且存在引发严重不良反应的风险。外科手术目前仍是唯一可实现长期有效减重的治疗手段。作为一种差异化且互补的干预手段，生活方式干预（包括摄入功能性食品（functional foods））可实现肥胖的可靠缓解，并降低共病发生风险。本研究所涉及的功能性食品包括浆果、蔬菜、高纤维谷物，饮品则涵盖茶与咖啡。本研究同时聚焦炎症性疾病动物模型的构建，所覆盖的炎症性疾病包括炎症性肠病、慢性肾病与关节炎。后续将利用这些模型探究功能性食品对上述病症的缓解作用。