Genome-wide mRNA profiling of styrene oxide effects in human induced pluripotent stem cells-derived neurons
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=2bc7f221e61aedf55f1a5abf7787d823
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资源简介:
In this study, we used human cortical neurons derived from induced pluripotent stem cell lines (N1) to identify universal transcriptomic signatures of styrene oxide neurotoxicity, to highlight novel pathways responsible for its biological activity, and to unravel potential associations with autism spectrum disorders. Total RNA was extrated from cells after 24h exposure to 100μM styrene oxide or vehicle and subjected to RNA sequencing.
提供机构:
Johns Hopkins School of Medicine
创建时间:
2022-02-20



