IGF2BP1 represses translation of MAPK4 mRNA
收藏reactome.org2025-01-16 收录
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Binding of IGF2BP1 to the 3' UTR of MAPK4 mRNA inhibits its translation and in this way antagonizes the MAPKAPK5-dependent phosphorylation of HSBP1 (Stohr et al, 2012; Kostenko et al, 2009a; reviewed in Kostenko et al, 2012).
IGF2BP1与MAPK4 mRNA的3'非编码区结合,抑制其翻译,从而拮抗了MAPKAPK5依赖的HSBP1磷酸化(参见Stohr等,2012;Kostenko等,2009a;Kostenko等,2012年综述)。
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