Pre-activated anti-viral innate immunity in the upper airways controls early SARS-CoV-2 infection in children

This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of of adults and children with COVID-19 (n=24 and n=21, respectively) and SARS-CoV-2-negative controls in each age group (n=23 and 18, respectively).An in-depth description is presented in the manuscript "Pre-activated anti-viral innate immunity in the upper airways controls early SARS-CoV-2 infection in children" (https://www.medrxiv.org/content/10.1101/2021.06.24.21259087v1).本数据集涵盖新型冠状病毒肺炎（COVID-19）成人及儿童患者的鼻咽样本单细胞RNA测序（single-cell RNA-Seq）数据，其中成人病例组样本量为24例，儿童病例组为21例；各年龄组对应的SARS-CoV-2阴性对照组样本量分别为23例与18例。该数据集的详细描述已发表于预印本论文《上呼吸道预激活的抗病毒先天免疫可控制儿童早期SARS-CoV-2感染》（https://www.medrxiv.org/content/10.1101/2021.06.24.21259087v1）。