Spatial microniches of IL-2 synergize with IL-10 to drive lung migratory Th2 cells in response to inhaled allergen

NIAID Data Ecosystem2026-05-01 收录

免疫细胞空间微环境

过敏性气道炎症

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE245112 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-02-27

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Memory helper T cells provide long-lasting host defeMemory helper T cells provide long-lasting host defense against microbial pathogens, while distinct subpopulations of memory T cells drive chronic i

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Nrp1 downregulation correlates with enhanced ILC2 responses during IL-33 challenge

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Group 2 innate lymphoid cells (ILC2s) play critical roles in driving the pathogenesis of allergic airway inflammation. The mechanisms underlying the regulation of ILC2s remain to be fully understood.

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Effects of aeroallergen challenge on inducible and constitutive lower airway mast cells. Effects of aeroallergen challenge on inducible and constitutive lower airway mast cells

过敏性气道炎症

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This study are compares the transcriptomes of lower airway constitutive connective tissue mast cells (MCs), characterized by low expression of b7 integrin (B7low), and induced mucosal MCs, characteriz

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Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses. Increased Hematopoietic Extracellular RNAs and Vesicles in the Lung during Allergic Airway Responses

过敏性气道炎症

"RNA研究"

Extracellular RNAs (exRNAs) can be released by numerous cell types in vitro, are often protected within vesicles, and can modify recipient cell function. To determine how the composition and cellular

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Bulk RNA-Seq of lung Type 2 Innate Lymphoid cells (ILC2) in response to Alternaria alternata

过敏性气道炎症

免疫细胞转录组学

Type 2 Innate Lymphoid cells (ILC2) play a crucial role in allergic airway inflammation. To identify transcriptional differences between naive ILC2 and allergen induced ILC2, mice were challenged wit

NIAID Data Ecosystem40

Spatial microniches of IL-2 synergize with IL-10 to drive lung migratory Th2 cells in response to inhaled allergen

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