Supplementary Materials for «Tri-Score+ и SR-Trachea: измерение результата и поддержка решения в реконструктивной хирургии рубцового стеноза трахеи»

Supplementary materials accompanying the paper «Tri-Score+ и SR-Trachea: измерение результата и поддержка решения в реконструктивной хирургии рубцового стеноза трахеи» submitted to Head and Neck Russian Journal (hnj.science). Includes: (1) full Open Science Framework pre-registration v3 with amendments (osf.io/a5ky3, registered 6 May 2026); (2) SAMPL-compliant statistical analysis detail; (3) COSMIN checklist for Tri-Score+; (4) Reilly & Evans 2006 clinical decision tool framework positioning for SR-Trachea; (5) sensitivity analyses SA1–SA5; (6) added-value reframing on mMRC standalone vs Tri-Score+ binary discrimination; (7) multiple imputation rationale; (8) supplementary figures S1–S4 (domain histograms, time-to-event distribution, continuous SR + LOESS, Kaplan–Meier by phenotype with number-at-risk table — removed from main text); (9) Python analysis code with fixed seed for reproducibility (block1–block7, figure rendering scripts); (10) cleaned analytical database (analytical_db_v2.xlsx) and computational outputs (results.xlsx). Reproducibility: Python 3.11+, fixed random seed = 42. License: CC-BY 4.0.本材料为提交至《Head and Neck Russian Journal (hnj.science)》的论文《Tri-Score+与SR-Trachea：瘢痕性气管狭窄重建手术的疗效评估与决策支持》的补充资料。包含以下内容：(1) 带修订内容的完整开放科学框架（Open Science Framework, OSF）预注册v3版本（注册链接osf.io/a5ky3，注册日期2026年5月6日）；(2) 符合SAMPL标准的统计学分析细节；(3) 针对Tri-Score+的COSMIN检查表；(4) SR-Trachea所对应的Reilly与Evans于2006年提出的临床决策工具框架定位；(5) 敏感性分析SA1至SA5；(6) 改良医学研究理事会呼吸困难指数（modified Medical Research Council, mMRC）单独使用与Tri-Score+二元判别法的附加价值重述；(7) 多重插补原理说明；(8) 补充图表S1至S4（包括领域直方图、事件发生时间分布、连续生存率（Survival Rate, SR）+局部加权回归散点平滑法（LOESS）、按表型分组的Kaplan-Meier生存曲线及风险人数表——已从正文中移除）；(9) 用于可复现性研究的固定随机种子Python分析代码（分为block1至block7，含图表生成脚本）；(10) 清洗后的分析数据库（analytical_db_v2.xlsx）及计算结果文件（results.xlsx）。可复现性说明：需使用Python 3.11及以上版本，固定随机种子为42。许可证：CC-BY 4.0。