Relationship between maternal exposure to life events and risk of offspring ASD with or without intellectual disability in the Stockholm Youth Cohort.
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Legend: Conditional logistic regression models estimating association of mother's experience of a serious life event and risk of ASD with and without intellectual disability in the Stockholm Youth Cohort.Footnote:OR = Odds Ratio, 95% CI = 95% Confidence Interval.*Model 1: adjusted for age of mother and father at birth of child, parity, quintiles of family disposable income adjusted for family size, highest educational qualification of mother or father, occupational class (highest of mother or father), migration status of parents.#Model 2: Model 1 further adjusted for occurrence of life events at other time points under study.
说明:本研究采用条件logistic回归(conditional logistic regression)模型,评估斯德哥尔摩青年队列(Stockholm Youth Cohort)中,母亲经历重大生活事件与伴/不伴智力障碍(intellectual disability)的自闭症谱系障碍(Autism Spectrum Disorder, ASD)发病风险之间的关联。 注:OR为比值比(Odds Ratio),95% CI为95%置信区间(95% Confidence Interval)。 *模型1:校正了子代出生时父母的年龄、产次、按家庭规模调整后的家庭可支配收入五分位数、父母双方最高学历、父母双方最高职业阶层以及父母移民身份。 #模型2:在模型1的基础上,进一步校正了研究覆盖的其他时间点发生的生活事件。



