Comparison of the L. braziliensis transcriptiome with published psoriasis datasets

Comparison of transcriptional responses in L. braziliensis lesions with published psoriasis meta-analysis. Log2 FC in gene expression between skin lesion and normal control skin for 17,070 genes in common between the L. braziliensis data and published psoriasis ‘MAD3’ data. Rank order is shown for both Leishmania and psoriasis data in which genes were ranked from most highly upregulated in lesion (rank = 1) to most downregulated in lesion (rank = 17,070). Abbreviations: FC, fold change本研究对比巴西利什曼原虫（L. braziliensis）皮损的转录应答与已发表的银屑病荟萃分析结果。针对巴西利什曼原虫数据集与已发表的银屑病"MAD3"数据集共有的17070个基因，计算其皮损与正常对照皮肤间的基因表达log2倍变化（log2 FC）。利什曼原虫与银屑病数据集均采用统一的基因排序规则：以皮损中上调最显著的基因为第1位，下调最显著的基因为第17070位。缩写说明：FC即倍变化（fold change）。