Replication in Cardiogenics of the miSNPs × 3utrSNPs detected in Gutenberg Health Study.

(1) Regression coefficient of the interaction term when both miSNP and 3utr proxy SNPs coded 0/1/2 according to the number of carried rare alleles are introduced in a linear regression model together with their interaction term.(2) P-value of the interaction test obtained in GHS when the Levene test p-value was used under a weighted-Bonferroni framework.(3) P-value of the interaction test derived from the standard linear regression analysis in Cardiogenics. Bold p-values are significant after Bonferroni correction.(1) 将miSNP与3'UTR代理单核苷酸多态性（3'UTR proxy SNPs）按照携带稀有等位基因的数量编码为0/1/2后，将二者及其交互项一同纳入线性回归模型，此时得到的交互项回归系数。(2) 在加权Bonferroni框架下采用Levene检验（Levene test）P值时，于GHS中得到的交互检验P值。(3) 由Cardiogenics数据集的标准线性回归分析推导得到的交互检验P值；经Bonferroni校正（Bonferroni correction）后仍显著的P值以粗体标注。