DETERMINANTS OF QUALITY OF LIFE AND TREATMENT SUSTAINABILITY IN PATIENTS UNDERGOING PERITONEAL DIALYSIS: A STUDY OF PSYCHOSOCIAL ADAPTATION AND LONG-TERM OUTCOMES

Chronic kidney disease represents a progressive and irreversible decline in renal function that affects millions of individuals worldwide and constitutes a major public health burden. As kidney function deteriorates to the stage defined as end-stage renal disease, patients require renal replacement therapy to survive. Traditionally, in-center hemodialysis has been the dominant modality; however, over the past decades, peritoneal dialysis has emerged as a viable and, in many cases, advantageous alternative. Peritoneal dialysis offers greater flexibility, home-based management, and increased autonomy, which may profoundly influence patients’ physical, psychological, and social well-being. Despite these potential advantages, the lived experience of individuals undergoing long-term peritoneal dialysis remains complex and multifaceted.慢性肾脏病（Chronic Kidney Disease）是一种进行性且不可逆的肾功能减退疾病，全球有数百万人群受其累及，构成了重大的公共卫生负担。当肾功能恶化至终末期肾病（End-Stage Renal Disease）阶段时，患者需接受肾脏替代治疗方可维持生存。传统上，中心血液透析（In-center Hemodialysis）一直是主流治疗手段；但在过去数十年间，腹膜透析（Peritoneal Dialysis）已成为一种可行且在多数场景下更具优势的替代疗法。腹膜透析可提供更高的治疗灵活性、支持居家管理，并提升患者的自主性，这些特性可对患者的生理、心理与社会福祉产生深远影响。尽管具备这些潜在优势，长期接受腹膜透析的患者的真实生活体验依然复杂且具有多面性。