Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one

Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoro-1,2-dihydropyrimidin-2-one Descriptor: 5-fluoropyrimidin-2-ol, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase Authors: Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. Deposit date: 2017-10-27 Release date: 2018-11-07 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.921 Å) Cite: Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 5-fluoropyrimidin-1-ium-2-olate To Be Published曼氏血吸虫（Schistosoma mansoni）来源的嘌呤核苷磷酸化酶（Purine nucleoside phosphorylase）同工型2与5-氟-1,2-二氢嘧啶-2-酮复合物的晶体结构。配体组成：5-氟嘧啶-2-醇、二甲基亚砜、嘌呤核苷磷酸化酶。作者：Faheem M、Neto JB、Collins P、Pearce NM、Valadares NF、Bird L、Pereira HM、Delft FV、Barbosa JARG。提交日期：2017年10月27日；发布日期：2018年11月7日；最后更新日期：2024年10月23日。实验方法：X射线衍射（分辨率1.921埃）。引用文献：《曼氏血吸虫来源的嘌呤核苷磷酸化酶同工型2与5-氟嘧啶-1-鎓-2-醇盐复合物的晶体结构》（待发表）