Human NPCs were differentiated into a neuron-rich culture for 2 weeks and incubated in the presence of 5 ng/ml each of IL-1β or TNF-α for 18 h.

Induction of inflammatory mediators by IL-1β and TNF-α in differentiated human NPCs (Mean fold induction). RNA was isolated and an immune pathway-specific array was performed. Values represent mean fold induction over untreated control from four independent experiments. More than 100-fold inductions are shown in blue.白细胞介素1β（IL-1β）与肿瘤坏死因子α（TNF-α）在分化后的人神经祖细胞（Neural Progenitor Cells, NPCs）中诱导炎症介质的表达（平均诱导倍数）。实验提取细胞总RNA，并开展免疫通路特异性芯片检测。所有数值均为四次独立实验中，相较于未处理对照组的平均诱导倍数。诱导倍数超过100倍的结果以蓝色标注。