Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221

Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab b13 heavy chain, Fab b13 light chain, ... Authors: Chen, L, Kwon, Y.D, Zhou, T, Wu, X, O'Dell, S, Cavacini, L, Hessell, A.J, Pancera, M, Tang, M, Xu, L, Yang, Z.Y, Zhang, M.Y, Arthos, J, Burton, D.R, Dimitrov, D.S, Nabel, G.J, Posner, M, Sodroski, J, Wyatt, R, Mascola, J.R, Kwong, P.D. Deposit date: 2009-07-22 Release date: 2009-11-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science, 326, 2009

与CD4结合位点抗体b13形成复合物的HIV-gp120核心晶体结构，空间群为C2221。描述项：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、Fab b13重链、Fab b13轻链等。作者：Chen, L、Kwon, Y.D、Zhou, T、Wu, X、O'Dell, S、Cavacini, L、Hessell, A.J、Pancera, M、Tang, M、Xu, L、Yang, Z.Y、Zhang, M.Y、Arthos, J、Burton, D.R、Dimitrov, D.S、Nabel, G.J、Posner, M、Sodroski, J、Wyatt, R、Mascola, J.R、Kwong, P.D。提交日期：2009-07-22；发布日期：2009-11-17；末次修改日期：2024-11-20。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率3.2埃（Å）。引用文献：《HIV-1 gp120 CD4结合位点的免疫逃逸结构基础》（Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120），《科学》（Science），第326卷，2009年。