Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation (CTOT-09)

The study will compare how well transplanted kidneys work and the response of people's immune systems as tacrolimus, a calcineurin inhibitor (CNI), is withdrawn. In addition, this research study will evaluate whether reducing immunosuppression can decrease some of these side effects while still preventing rejection of the kidney.

本研究将对比撤除他克莫司（tacrolimus）——一种钙调磷酸酶抑制剂（calcineurin inhibitor, CNI）——后，移植肾的功能状态与人体免疫系统的应答情况。此外，本研究还将评估减少免疫抑制治疗是否能够在仍预防肾移植排斥反应的前提下，减轻部分此类不良反应。