Conservation of yeast proteins involved in N-linked glycosylation.

Genes are broadly categorized by function. Human genes are identified by name when possible and the corresponding congenital disorders of glycosylation (CDG, with OMIM ID) are shown. For A. thaliana, C. elegans, D. melanogaster, D. rerio, M. musculus, and P. falciparum, boxes marked with “x” indicate that a peptide from this organism was placed in the same OrthoMCL family with the yeast gene. Not shown: SWP1 is homologous to human ribophorin II [30], and SWP1, OST4, OST5, and OST6 do not lie in ortholog families.