Risk of bias from included studies.

ObjectiveThe systematic review aims to determine the safety of conducting non-upper airway surgery in an ambulatory surgery center (ASC) for OSA patients.Data sourcesA comprehensive search was conducted from MEDLINE, Embase, CENTRAL, and Scopus from inception through February 2023.Review methodsStudies including non-upper airway surgery done in ASC settings were identified. Risk of bias was assessed using the Murad Tool and Newcastle-Ottawa scale. Primary outcomes were 24 hour complications and unplanned admission rates.ResultsFrom 9313 studies, 13 non-OSA studies with 31,200 OSA participants and 318,709 non-OSA participants were identified. Severe complications were rare and tended to occur within the first 4 hours of the postoperative period. While a majority of smaller scale studies found no significant difference in unplanned admissions, large scale studies with multivariate analysis find OSA to be an independent risk factor for unplanned admission and 30-day complications. However, large scale ASC studies have found that with proper selection and perioperative interventions, OSA patients can undergo outpatient surgery at ASCs safely.ConclusionsOSA patients with mild or controlled comorbidities can safely undergo ambulatory non-OSA surgery in ASCs.OtherThe protocol for this review was registered with the PROSPERO database (Registration number: CRD42023415162).研究目的：本系统综述旨在明确阻塞性睡眠呼吸暂停（Obstructive Sleep Apnea, OSA）患者在门诊手术中心（Ambulatory Surgery Center, ASC）接受非上气道手术的安全性。 数据来源：本研究于建库时至2023年2月期间，对MEDLINE、Embase、CENTRAL及Scopus数据库进行了全面检索。 综述方法：筛选出在门诊手术中心环境下开展非上气道手术的相关研究，并采用Murad量表（Murad Tool）与纽卡斯尔-渥太华量表（Newcastle-Ottawa scale）对偏倚风险进行评估。本研究的主要结局指标为24小时内并发症发生率与非计划住院率。 研究结果：本研究从9313项文献中，最终纳入13项相关研究，共涉及31200名OSA患者与318709名非OSA患者。严重并发症极为罕见，且多发生于术后前4小时内。多数小规模研究未发现非计划住院率存在显著差异，但开展多变量分析的大规模研究则显示，OSA是非计划住院与30天并发症的独立危险因素。不过，大型ASC相关研究表明，经合理筛选患者并实施围手术期干预后，OSA患者可安全地在门诊手术中心接受手术治疗。 研究结论：合并轻度共病或共病得到有效控制的OSA患者，可安全地在门诊手术中心接受非上气道门诊手术。 其他说明：本综述的研究方案已在PROSPERO数据库注册（注册编号：CRD42023415162）。