Establishment and characterization of an Epstein-Barr virus-positive cell line from a non-keratinizing differentiated primary nasopharyngeal carcinoma

Supplementary Dataset 1 - List of filtered SNPs in NPC268 tumor and cell line. <br> Supplementary Dataset 2 - JSON file containing the interactive dataset of the 125 compounds lnIC50 in 7 NPC cell lines, to be loaded and view as heatmap on Morpheus (Broad Institute) (https://software.broadinstitute.org/morpheus/) <br> Supplementary Dataset 3 - NPC268 and other NP/NPC lines' RNA-seq data Combat corrected IRAP RNA-seq - log2FPKM QN - 8 NP and NPC lines <br> Others: <strong>NPC268 WGS data - VCF files for unfiltered SNPs</strong> NPC268_Cell_line.GATK.snp.vcf NPC268_Tumor.GATK.snp.vcf <br> <strong>NPC268 WGS data - VCF files mapped to EBV genome</strong> NPC268_GATK_haploid_BQSR_SNPsINDELs_filtered_selected_nonmask.vcf <br> <br> <strong>NPC268 WGBS data </strong> NPC268.bigwig <br> <br>补充数据集1：NPC268肿瘤组织与细胞系中经过滤的单核苷酸多态性（Single Nucleotide Polymorphism, SNP）列表。 补充数据集2：JSON格式文件，包含7株NPC细胞系中125种化合物的半数抑制浓度自然对数（lnIC50）交互式数据集，可在布罗德研究所（Broad Institute）开发的Morpheus平台（https://software.broadinstitute.org/morpheus/）中加载并以热图形式展示。 补充数据集3：涵盖8株NP与NPC细胞系的NPC268及其他NP/NPC细胞系RNA测序（RNA-sequencing, RNA-seq）数据，具体为经Combat校正的IRAP RNA-seq数据集，采用log2FPKM分位数归一化（Quantile Normalization, QN）处理。 其他数据集： **NPC268全基因组测序（Whole Genome Sequencing, WGS）数据——未过滤单核苷酸多态性的VCF（Variant Call Format, VCF）文件**：NPC268_Cell_line.GATK.snp.vcf、NPC268_Tumor.GATK.snp.vcf **NPC268全基因组测序数据——比对至EB病毒（Epstein-Barr Virus, EBV）基因组的VCF文件**：NPC268_GATK_haploid_BQSR_SNPsINDELs_filtered_selected_nonmask.vcf **NPC268全基因组亚硫酸氢盐测序（Whole Genome Bisulfite Sequencing, WGBS）数据**：NPC268.bigwig