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Data for: Synthesis, biological evaluation, and molecular docking study of novel allyl-retrochalcones as a new class of protein tyrosine phosphatase 1B inhibitors

Mendeley Data2019-02-06 更新2026-04-09 收录

PTP1B抑制剂

分子药物设计

数据链接：

https://data.mendeley.com/datasets/5ymg9hf9sz 数据链接链接失效反馈

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资源简介：

Spectral data

光谱数据（Spectral data）

应用场景：

创建时间：

2019-02-06

分子药物设计

自身免疫疾病靶向治疗

Tumor necrosis factor α (TNFα) is a soluble cytokine that is directly involved in systemic inflammation through the regulation of the intracellular NF-κB and MAPK signaling pathways. The development o

NIAID Data Ecosystem100

Insights into membrane translocation of the cell-penetrating peptide pVEC from molecular dynamics calculations

细胞穿透肽机制

分子药物设计

Discovery of cargo carrying cell-penetrating peptides has opened a new gate in the development of peptide-based drugs that can effectively target intracellular enzymes. Success in application and deve

Figshare2016-09-30 更新60

Rotaxanating Metallo-supramolecular Nano-cylinder Helicates to Switch DNA Junction Binding

分子药物设计

DNA连接结构靶向

A class of rotaxane is created, not by encapsulating a conventional linear thread, but rather by wrapping a large cucurbit[10]uril macrocycle about a three-dimensional, cylindrical, nanosized, self-a

NIAID Data Ecosystem40

PTP inhibition improves the macrophage anti-tumor immune response and the efficacy of chemo- and radiotherapy [GeoMX profiling]. PTP inhibition improves the macrophage anti-tumor immune response and the efficacy of chemo- and radiotherapy [GeoMX profiling]

肿瘤免疫治疗

PTP1B抑制剂

Traditional anti-cancer therapies induce tumor cell death and subsequent release of Damage Associated Molecular Patterns (DAMPs) that activate the innate inflammatory response. Paradoxically, after tr

NIAID Data Ecosystem60

Structural determinants of Liver receptor X modulation (LXRalfa) – MD

核受体结构模拟

分子药物设计

Please check the readme file for the simulation descriptions

NIAID Data Ecosystem60