Additional file 7 of A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome

Additional file 7. Supplementary Table 5. This table shows the raw data for each CpG and each Phen#, success ratio was calculated as a proportion of #successful SNPs for that CpG to #all SNPs associated with that phenotype group, Phen#. “Success” means that the distance between location of a SNP and location of the CpG is less than the stated max distance. Series of incremental distances from 50,000 bp to 1,000 bp were tested, and then compared across the phenotype groups. The one-tailed Mann-Whitney U test was used to compare differences in success ratios between Phen1 and Phen 2 and “negative control” Phen4 as shown in Table 4.

附加文件7：补充表5。本表格展示了每一个CpG位点（CpG site）与每一个表型编号（Phen#）对应的原始数据。成功比率的计算方式为：针对该CpG位点的成功单核苷酸多态性（Single Nucleotide Polymorphism，SNP）数量，与该表型组（表型编号Phen#）关联的全部SNP数量的比值。此处的"成功"指单核苷酸多态性（SNP）的位点与CpG位点的间距小于设定的最大距离阈值。本次测试了从50,000碱基对（base pair，bp）到1,000碱基对（base pair，bp）的一系列递增间距，并在各表型组间开展对比。如表4所示，本研究采用单尾曼-惠特尼U检验（one-tailed Mann-Whitney U test），对比表型1（Phen1）、表型2（Phen2）与"阴性对照"表型4（Phen4）之间的成功比率差异。