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Abnormal Transcriptome-wide of DNA demethylation in Folate deficiency caused neural tube defects [ChIP-seq]

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https://www.ncbi.nlm.nih.gov/sra/SRP377191
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资源简介:
To investigate the associated with DNA demethylation and neural tube defects (NTDs) with folate deficiency, we etablished mouse embryonic stem cells (mESCs) Sv/129 in folate-deficiency-treated. Overall design: We then performed the enrichment of H3K27ac analysis using data obtained from H3K27ac ChIP-seq in the cell model. Comparative the enrichment of H3K27ac analysis of ChIP-seq data for sv129 cells as control group and its folate-deficiency-treated as experimental group.
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2022-09-21
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