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Widespread epistasis among beneficial genetic variants revealed by high-throughput genome editing

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NIAID Data Ecosystem2026-03-14 收录
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We employed CRISPEY-BAR, a high-throughput precision genome editing technology to measure the fitness effects of 1,826 naturally polymorphic variants in four genetically diverse strains of Saccharomyces cerevisiae, as well as quantify the extent of epistasis due to genetic background.

创建时间:
2022-12-18
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