Data record for the article: Drivers of Genomic Loss of Heterozygosity in Leiomyosarcoma are Distinct from Carcinomas

This record provides details of the data supporting the claims of the related article: "Drivers of Genomic Loss of Heterozygosity in Leiomyosarcoma are Distinct from Carcinomas". This related study aimed to define loss of heterozygosity to support the use of precision medicine in the development of therapeutics for leiomyosarcomas.<br>Type of data: Genomic profiling data, copy number data; limited clinical dataSubject of data: leiomyosarcoma patientsSample size: 1,658 retrospectively analyzed samples<br><b>Data access</b>The genomic profiling of pathogenic variants in leiomyosarcomas are openly available as part of this figshare metadata record in the files ‘Clinical Data.xlsx" and "Genomic Data.xlsx".<br><b>Corresponding author for this study</b>James L. Chen ([e-mail])<br><b>Study approval</b>Western Institutional Review Board (protocol No. 20152817)

本数据集记录详细阐明了支撑相关学术论文核心结论的全部数据，该论文标题为《平滑肌肉瘤基因组杂合性缺失（Genomic Loss of Heterozygosity）的驱动因素与癌类存在差异》。本研究旨在明确杂合性缺失的相关特征，以推动精准医学在平滑肌肉瘤治疗药物研发中的应用。
数据类型：基因组谱分析数据、拷贝数数据及有限临床数据
数据研究对象：平滑肌肉瘤患者
样本规模：共计1658例经回顾性分析的样本
【数据获取】
平滑肌肉瘤致病变异的基因组谱分析数据可通过本figshare元数据记录中的"Clinical Data.xlsx"与"Genomic Data.xlsx"文件公开获取。
【本研究通讯作者】
詹姆斯·L·陈（[e-mail]）
【研究伦理审批】
西部机构审查委员会（伦理审查编号：20152817）