Rnf146

Predicted to enable enzyme binding activity; poly-ADP-D-ribose binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to hydrogen peroxide; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and genitourinary system. Used to study osteochondrodysplasia. Orthologous to human RNF146 (ring finger protein 146). [provided by Alliance of Genome Resources, Nov 2024]

该数据集预测可激活酶的结合活性、多聚-ADP-核糖结合活性和泛素-蛋白转移酶活性。预测其参与多个生物学过程，包括细胞对过氧化氢的响应、经典Wnt信号通路的正向调控以及蛋白质泛素化。预测其定位于细胞质、核浆和质膜。预测其在细胞质和细胞核中活跃。在中央神经系统及泌尿生殖系统中表达。用于研究骨软骨发育不良。与人类RNF146（环指蛋白146）同源。[由基因组资源联盟提供，2024年11月]