Project_09 Q24 StudyTitle Probing the environmental modulation of sensitization and compulsive checking: effects of a walled circular arena

This study (Q24) is one of a series of studies performed in the Szechtman lab at McMaster University and deposited in the FRDR public repository as a collection under the name "A Digital Library of Behavioural Performance in Standardized Conditions - Szechtman Lab Collection". This collection as a whole constitutes a big dataset containing raw data objects of video, track, and path plot records of rats exploring for 55 minutes a large testing environment in a standardized paradigm during chronic treatment with psychostimulant drugs; for details of this big dataset see, https://www.frdr-dfdr.ca/repo/collection/szechtmanlab. The historical context for study Q24 was Project_09 entitled: "Probing the environmental modulation of sensitization and compulsive checking". Title of experiment in Q24 was "Effect of a circular arena on development of sensitization and compulsive checking induced by QNP (0.5 mg/kg)". Rather than using our standard open field with 4 objects in it, this study examined during the course of 10 trials the development of the response to quinpirole (0.5 mg/kg) in rats tested in a large empty circular arena with walls.

本研究（Q24）是麦克马斯特大学塞赫特曼实验室开展的系列研究之一，已以“标准化条件下行为表现数字馆藏——塞赫特曼实验室数据集”为名存入FRDR公共存储库。该数据集整体为大型数据集，包含大鼠在精神兴奋剂类药物慢性给药处理下，于标准化实验范式中在大型测试环境内探索55分钟的视频、运动轨迹与路径绘图记录等原始数据对象。有关该大型数据集的详细信息，请访问：https://www.frdr-dfdr.ca/repo/collection/szechtmanlab。Q24研究的背景为题为“探究敏化与强迫性检查行为的环境调控机制”的项目09。Q24的实验标题为“圆形开阔场对喹吡罗（QNP，0.5mg/kg）诱导的敏化与强迫性检查行为发展的影响”。本研究未采用本实验室常规使用的配备4个物体的开放场箱，而是在10轮实验试次中，对置于带围墙的大型空圆形开阔场中的大鼠进行喹吡罗（0.5mg/kg）给药后的反应发展情况进行了考察。