Tl amd dl mediate the Aβ42 induced rough eye phenotype.

The rough eye phenotype of pGMR-Aβ42 flies was assigned a value of ++++. According to this scoring system, strong, moderate and weak suppression corresponded to +, ++, and +++ respectively. Weak and moderate enhancement corresponded to +++++ and ++++++. All flies are hemizygous for the transgene and either wild type (+) or heterozygous for the indicated mutation. In the experiment with the hsp83:dl transgene the flies are hemizygous for this transgene.